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Cytomegalovirus and human immunodeficiency virus in semen of homosexual men

Objective: To assess the accuracy of serology to predict the presence of cytomegalovirus (CMV) in semen of homosexual men without and with HIV coinfection. Results: Cytomegalovirus was detected by electron microscopy in 3 of 10 specimens examined. Forty-six (89%) of 52 HIV-infected men were seropositive for CMV by combined assay for IgG/IgM; two more (48…

HIV-1 in semen: an isolated virus reservoir

The reservoir of HIV-1 in semen is unknown. Semen is comprised of secretions and cells from seminal vesicles, prostate, testis, epididymis, and ejaculatory ducts; leucocytes are present in semen, although their source and their role in the semen viral burden is unclear. Reports that semen viral RNA concentrations do not correlate with those in plasma,…