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What is Gene-Editing?

Is gene editing human embryos a positive scientific breakthrough for human health, or misuse of a powerful research tool? Over the next six months, we will outline the basic biology behind gene editing, followed by a description of the process in general and in human embryos, specifically.

Volunteer of the Year

We are very grateful for the help from our Volunteer of the Year, Deborah Weidman. A Bedford High School student, she has been instrumental to our circadian rhythms in stem cells research this year. She is planning to use her experience with BRF in her career in biomedical engineering. Thank you Deborah!

Prostate Disease Research Update

Patient recruitment into the prostate cancer screening project is ongoing, and Bedford Research Scientists have developed methods for including specimens submitted to the laboratory for other types of testing.  The goal of the project is to develop semen screening tests that improve diagnosis and staging of prostate cancer as well as reflect overall male health….

Meet Dr. Aparajita Chatterjee

Dr Chatterjee, a Bedford resident, joins us from Boston Medical Center where she conducted infectious disease research for six years. A skilled molecular biologist and cell culture expert, she is spearheading the work to identify and characterize successful gene silencing in our mouse model parthenote stem cells. We are fortunate to have her.

Bedford Research Launches New Stem Cell Program

Dr. Joel Lawitts microinjects gene editing enzymes into unfertilized mouse eggs to neutralize a major histocompatibility gene that leads to tissue rejection in unmatched individuals. This is the first step in generating off-the-shelf stem cells for everybody. “Dr. Kiessling and her staff have shown their determination to tackle some of the most difficult health problems…

From the Director

It is finally all coming together… My career in reproductive biology and AIDS began in 1983, with the goal of understanding the influence of viruses on early embryo development. Wonderful young scientists joined my laboratory for periods of training during the ensuing 33 years, and together we have made many discoveries that bring our laboratory…

BRF Wraps Up Community Consulting Teams (CCT) Project

For the past several months Bedford Research Foundation has been working with Community Consulting Teams (www.cctboston.org) to complete a Strategic Assessment designed to help the foundation strengthen and improve communications surrounding both short and long term research projects. As part of this process, CCT has assisted the BRF in studying the potential future impacts of the work the foundation is doing. On June 9th,…

Bedford Research Foundation Open House Next Week!

The Bedford Research Foundation (BRF) is hosting two open houses Thursday, April 30 from 5:30 – 8:00 pm, and Saturday, May 2 from 4:00 – 6:00 pm for local residents and members of the biomedical, healthcare, and manufacturing industries. The event is open to the public and includes a short presentation by foundation director, Dr….