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Microarray evidence that 8‑cell human embryos express some hormone family members including oxytocin

Abstract Objective This study is to discover hormone pathways active in early cleaving human embryos. Methods A list of 152 hormones and receptors were compiled to query the microarray database of mRNAs in 8-cell human embryos, two lines of human embryonic stem cells plus human fibroblasts before and after induced pluripotency. Results Over half of the…

2011 Newsletter: Progress in Circadian Rhythms And Stem Cells

BRF scientists have derived two unique lines of stem cells that may lead to a breakthrough in the efficiency of stem cell derivation and expansion. BRF scientists are following up their discovery that the genes that regulate the rhythms of daily life, circadian rhythm genes, may play important roles in stem cell derivation and stability…