Dr. Mario Capecchi will keynote the tenth annual Symposium. Dr. Capecchi is a Distinguished Professor of Human Genetics & Biology at the University of Utah School of Medicine, an Investigator with the Howard Hughes Medical Institute, as well as a 2007 Nobel Laureate for Physiology & Medicine.
Dr. Capecchi is best known for his pioneering work on the development of "gene targeting" in mouse embryonic stem (ES) cells. This technology allows scientists to create mice with mutations in any desired gene. The power of this technology is that the investigator chooses both which gene to mutate and how to mutate it. This allows scientists to evaluate in detail the function of any gene during the development or post-developmental phase of the mouse.