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Dr. Capecchi is best known for his pioneering work on the development of "gene targeting" in mouse embryonic stem (ES) cells. This technology allows scientists to create mice with mutations in any desired gene. The power of this technology is that the investigator chooses both which gene to mutate and how to mutate it. This allows scientists to evaluate in detail the function of any gene during the development or post-developmental phase of the mouse. |






















































































































