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Science Highlights – October 2017

Circadian Rhythms in the Spotlight The 2017 Nobel Prize in Physiology for circadian rhythm discoveries is exciting news for Bedford Research. Almost a decade ago, Bedford Research scientists discovered circadian rhythm genes were turned on as early as three days (the 8-Cell stage) after a human egg was activated by sperm (1). Although circadian rhythms…

To PSA or Not to PSA: That is the Question

By Ann A. Kiessling, PhD Download this article (pdf) The current raucous debate over the commonly used PSA blood test to screen for prostate cancer, the third leading cause of cancer deaths in men in the U.S.(a), stems from the U.S. Preventive Services Task Force’s recommendation to discontinue PSA screening(b). The debate is pitting physician…

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The History of the Dickey-Wicker Amendment

Ann A. Kiessling, PhD     Federal concern with human embryo research began over 25 years ago with the advent of assisted reproduction technologies, i.e. in vitro fertilization (IVF) or “test tube babies.” Although the first report of laboratory studies of human fertilization appeared in Science in 1944, (the work was conducted in Brookline, Massachusetts),…

Curing HIV Disease With Stem Cell Therapy

Science Highlights by Ann A. Kiessling, PhD Download this article What is HIV disease? Human Immunodeficiency Virus (HIV) infects specific types of cells in the immune system. Like most viruses, in order for HIV to infect a cell, the virus must bind to a specific protein, termed a receptor, on the cell’s surface. There are…

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Patient-Specific, Pluripotent Stem Cells – Testis is a New Source

Science Highlights by: Ann A. Kiessling, PhD Download this article Improving treatments for damaged organs and tissues is the promise of human pluripotent stem cells. The power of pluripotent stem cells to alleviate damage to organs, a form of regenerative medicine, has been amply demonstrated in many animal and laboratory model systems (see: State of the…

The State of the Stem Cell

Science Highlights by Ann A. Kiessling, PhD Download this article PDF Too many choices? The big question facing scientists is: what type of pluripotent stem cell will ultimately prove to be the most therapeutically valuable? As we enter a new decade of this new millennium, stem cell science is in a state of confusion. The…

Can stem cells cure HIV?

Ann A. Kiessling, PhD   A promising new case report of stem cell therapy for leukemia re-opens the possibility of curing HIV infection with stem cell transplantation Revisiting HIV and Stem Cells In February, 2009, a medical team in Germany (N Engl J Med 360(7):692; February 12, 2009) reported that their treatment for leukemia in…